Journal Top Ten -- COLUMNS-Asbestos -- December 2005

1 TITLE: "Interaction of Bovine Serum Albumin with Chrysotile: Spectroscopic and Morphological Studies"

AUTHORS:Not Available

JOURNAL: Chemistry. 2005 Dec 16; [Epub ahead of print]

SUMMARY: The biodurability of chrysotile fibers, which is related to their cytotoxicity and mutagenic responses, is strongly affected by the surface chemical adsorption of biological molecules. Natural chrysotile is a heterogeneous material in both structure and composition. The availability of synthetic stoichiometric chrysotile of constant structure and uniform morphology has allowed us to investigate its interaction with bovine serum albumin (BSA). Synthetic stoichiometric chrysotile nanocrystals were shown to be an ideal reference standard …