Journal Top Ten -- COLUMNS-Drugs & Supplements --February 2008

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SSRIs

ARTICLE: 'Risks Of Suicide and Poisoning Among Elderly Patients Prescribed Selective Serotonin Reuptake Inhibitors'

JOURNAL: The Journal of Clinical Psychiatry 2008 Feb 13;:e-1-e9

SUMMARY: This study examines records of 128,229 patients 65 years and older who were prescribed serotonin reuptake inhibitors between January 1998 and December 2004. Risks of suicide and poisoning were compared during periods when the patients were treated with an SSRI against periods with no antidepressant treatment. The authors found the adjusted risk of suicide was not higher during SSRI use versus non-use, but the adjusted hazard ratio of poisoning …