Journal Top Ten -- COLUMNS-Drugs & Supplements --December 2007

1
Seroquel

ARTICLE: 'Quetiapine-induced Leucopenia and Thromobcytopenia'

JOURNAL: Psychosomatics 2007 Nov-Dec;48(6):530-1

SUMMARY: The report identifies a case of leucocytopenia and thrombocytopenia associated with Seroquel treatment, despite prevailing medical data indicating that newer atypical antipsychotics do not cause adverse hematological side effects. The other notes that older, similar drugs can cause neutorpenia, which can progress to life-threatening complications if the treatment is not discontinued.

AUTHORS: B.R. Shankar

WEB SITE: http://psy.psychiatryonline.org/

2
Avandia/Actos

ARTICLE: 'Thiazolidinediones and Cardiovascular Outcomes in Older Patients with Diabetes'

JOURNAL: JAMA 2007 Dec 12;298(22):2634-43

SUMMARY: To explore the association between Thiazolidinedione …